The presence of ketone bodies in the urine of diabetic patients may indicate poor glycemic control, which can usually be eliminated by actively controlling blood glucose as prescribed by the doctor. Ketone bodies come from lipolysis, when insulin deficiency or insulin resistance is severe, the body is unable to utilize glucose for energy supply, then the breakdown of fat increases, which may lead to ketone bodies in the urine. When ketone bodies appear in the urine of diabetic patients, it suggests that the blood glucose control may be poor, need to follow the medical advice to use metformin, acarbose or insulin injection to control blood glucose, at the same time need to control the diet, reasonable exercise, through a comprehensive treatment of blood glucose control to meet the standard, the ketone bodies in the urine tend to gradually disappear. When ketone bodies are found in the urine of diabetic patients, they should seek medical treatment in time to avoid delaying their condition.