Patient: The patient is a female, 77 years old, diagnosed with paroxysmal atrial fibrillation at Xinhua Hospital two years ago. However, after examination, she was found to have a thickened left ventricle with thrombus (small left ear thrombus) and was ruled unable to undergo catheter ablation. Is there any medication that can be recommended and is catheter ablation not possible if there is a small thrombus in the left heart ear? The first people’s hospital in Shanghai, the Department of Cardiology, Liu Shao steady: 1, if not to do catheter ablation, atrial fibrillation treatment principle is to control the ventricular rate, the second is anticoagulation (CHADS2 classification 2 or more). 2, to strict anticoagulation standards for more than 3 months to see if the thrombus can disappear.