Tubular adenoma is generally a benign lesion and belongs to one of the colorectal adenomas due to abnormal glandular proliferation, while low-grade intraepithelial neoplasia belongs to a milder category of precancerous lesions with a lower possibility of carcinogenesis, the etiology of which is still unclear and is mainly considered to be related to human papilloma virus infection, and may also be associated with smoking, long-term use of immunosuppressive drugs, and genetic factors. Therefore, tubular adenoma with low-grade intraepithelial neoplasia is generally a benign condition, which can be manifested as mucosal projections of different sizes, pink in color and soft in texture, and patients can have symptoms such as diarrhea, blood in stool and abdominal pain, etc. Specific treatment should be decided according to the size of tubular adenoma. 1. The patient needs to review the colonoscopy regularly and use Chinese herbal medicine to control the development of the disease, mainly detoxification and blood stasis drugs, and also injection therapy to make the tubular adenoma necrotic and fall off. The surgical procedure depends on the surgeon’s judgment. Tubular adenoma with low-grade intraepithelial neoplasia is generally benign, but in a few cases there is a risk of malignancy, so a biopsy should be done to determine the nature of the excised area. If the tumor is malignant, it is necessary to determine whether chemotherapy or radiotherapy is needed after surgery according to the specific progress of the tumor.