Women are a special group, with a special endocrine system and physiological cycle, and are also responsible for the difficult task of pregnancy and breastfeeding. In addition, women have higher demands on their appearance, body shape and skin. Therefore, for women with epilepsy, our doctors should give more thoughtful consideration to the selection of epilepsy drugs. Long-term clinical applications and studies have shown that the side effects of valproic acid drugs include rash, allergy, gastrointestinal reactions, drowsiness, endocrine reactions, and drug-related liver damage. The probability of these side effects is not high, and some patients who tolerate well feel nothing after taking the drug. For female patients, some may experience obesity, enlarged pores, acne, irregular menstruation, ovarian cysts, fetal abnormalities, etc. My experience is that women with epilepsy try not to prefer valproate at the beginning, and if other medications feel out of control after a while and valproate can be well controlled, you can gradually increase the dose to the lowest dose to maintain it. If the first consultation is not with me and someone else gives valproic acid, you can assess the control and side effects of the drug and, if the situation allows, gradually reduce and stop the drug with less side effects. In particular, women with childbearing requirements should gradually stop taking the drug six months before pregnancy under the guidance of a doctor to prevent possible abnormalities in fetal growth and development.