Rheumatoid arthritis in the elderly is usually divided into two clinical types: 1. A type of rheumatoid arthritis that attacks in the elderly, i.e., rheumatoid arthritis that attacks only at the age of 60-65 years. This type is mostly seen in women, with acute onset and often accompanied by significant weight loss. The large joints, especially the shoulder, are more prominently involved. Morning stiffness, limited joint movement and soft tissue swelling are more obvious, and laboratory disease activity indicators such as blood sedimentation is significantly elevated, but negative rheumatoid factor is more common. 2. The second type of senile rheumatoid arthritis is one that strikes before the age of 65 and persists until after 65. Most patients with this type have a decades-long history of active rheumatoid arthritis, resulting in significant joint disability. This group of patients is often treated with multiple medications simultaneously.