Acute urticaria treatment with hormone injections may have certain adverse effects on the body, but as long as the standardized use of medication, the overall benefits outweigh the disadvantages. Acute urticaria is due to a variety of factors after the stimulation of vascular permeability increase and capillary dilatation, in the clinical mainly manifested in the skin surface of the temporary, limited and elevated erythema, which is generally given the conventional antihistamine drug treatment, the symptoms can be improved. Some patients with acute urticaria may involve the gastrointestinal mucosa, abdominal pain, diarrhea, nausea, vomiting and other gastrointestinal reactions, but also may involve the respiratory mucosa and respiratory difficulties, or even asphyxia, in this case, the timely use of glucocorticosteroid medication, can quickly reduce edema, relieve the symptoms of acute urticaria. Generally acute urticaria using hormone drugs dosage is small, and for temporary use, usually does not cause adverse effects on the body. Some patients may have elevated blood sugar, especially diabetic patients, should be used with caution. If glucocorticoid drugs are used in excess, they may lead to adverse reactions such as full moon face, weight gain, hirsutism, and osteoporosis. In order to minimize the adverse effects of the drug, it should always be used under the supervision of a doctor.