This is the most frequently asked question by patients and families in my clinical work. To answer this question, we should first talk about tumor grading and tumor staging, which are two completely different concepts. Neuroendocrine tumors, codenamed NET, like other malignant tumors, are diagnosed by pathology. (For those who know English, G stands for Grade. G1, G2 and G3 are the grades of tumors, reflecting the biological behavior of NET tumors, and the degree of malignancy, from low to high, is G1 < G2 < G3. <Therefore, NET G1 means that the tumor is less malignant and slower growing, which is different from metastasis or non-metastasis. All neuroendocrine tumors have malignant potential. Whether it metastasizes or not depends on the staging. The staging is based on the size of the tumor, whether it has metastasized to lymph nodes, whether it has metastasized to liver, lung, bone and other distant places, and is divided into stage 1, stage 2, stage 3 and stage 4 by clinicians. Various specific tumor staging standards are not quite the same. Broadly speaking, stage 1 and stage 2 belong to early stage, stage 3 and stage 4 belong to middle and late stage, for example, metastasis to liver belongs to stage 4. Therefore, tumor staging refers to whether the tumor patient has spread metastasis or not at the time of diagnosis, which is determined by the doctor after assessment based on CT, MRI, ultrasound and other examinations, and is two concepts different from G1, G2 and G3. G1 is G1, G2 is G2, and it has nothing to do with "stage". Now that we have clarified the difference between grading and staging, let's go back to the question: Why did we transfer NET G1? NETG1 refers to the tumor grade, which indicates that the tumor is less malignant, slower growing, does not metastasize in the early stage, and metastasizes in the late stage as well. It is not surprising when a NETG1 patient has metastasis, and it is not uncommon to see pancreatic NETG1 liver metastasis and rectal NETG1 liver metastasis in clinical practice. So here comes the question again. The most important thing is that the patient will be able to get the information from the Internet, but unfortunately, they do not know anything about medicine, and sometimes they know what they are hearing, and sometimes they do not know what they are hearing, which causes unnecessary anxiety or panic. Nowadays, there are many patients with rectal NETG1 anxiety, so we hope to spread more knowledge about it in the future. Generally speaking, rectal NETG1, tumor less than 1cm, can be cured by standard endoscopic treatment, there is no need to worry; but for tumor diameter ≥1cm should be closely followed up, here we emphasize the need for standardized follow-up review. Therefore, before the treatment of a NET tumor patient, the doctor should make a comprehensive assessment, including the grading and staging of the tumor, not only the pathological grading, but also the clinical staging. In conclusion, each NET patient's situation is not the same, and doctors will make a reasonable diagnosis and treatment plan according to the patient's different conditions.