Advantages of neoadjuvant chemotherapy 1.It can shrink the tumor and reduce the invasiveness, so that inoperable becomes operable; 2.It can detect the efficiency of chemotherapy regimen and is a testing ground for drug sensitivity; 3.It can reduce the tumor stage and can make a part of patients to preserve breast by surgery; 4.It can inhibit the bloodstream metastasis and lymphatic route metastasis, kill the systemic micro-metastasis and improve the long-term survival rate; 5.Patients who cannot be operated It can control metastasis and prolong the survival period. The shortcomings of neoadjuvant chemotherapy 1.Since chemotherapy reduces the clinical stage of tumor patients, it may cause confusion in postoperative treatment, and may cause problems in the choice of radiotherapy treatment; 2.Since patients have other underlying diseases, the side effects of chemotherapy may cause patients to lose the opportunity of surgery; 3.Since neoadjuvant chemotherapy is carried out in hospitals at all levels, the level varies; 4.It may cause patients’ medical expenses to increase. increase. Foreign experience, especially in the United States, half a century of research concluded that neoadjuvant therapy does not improve the overall survival rate, and neoadjuvant therapy and postoperative chemotherapy have the same survival rate.