Cancer pain is one of the most common, difficult to control and painful symptoms for cancer patients. According to statistics, about 50% to 80% of cancer patients have to suffer from different degrees of pain throughout the course of the disease along with the progress of the cancer and the deterioration of their physical condition after diagnosis. The pain will be further aggravated when the patients lose confidence in treatment and withdraw from social activities in the late stage of the disease. There are generally three causes of cancer pain: I. Cancer-related. The most common reasons are bone metastasis, compression of nerves or infiltration destroying nerves. Second, caused by anti-cancer treatment. Surgery, chemotherapy and radiotherapy inhibit the immune system and make patients susceptible to viral, bacterial and fungal infections causing pain, such as herpes zoster, chickenpox, etc. In addition, some examination means taken in diagnosing cancer can also cause a certain degree of pain, such as lumbar puncture to take cerebrospinal fluid, blood specimen, angiography, endoscopy and tissue biopsy. Comorbidities not related to cancer. The pain can be caused by concurrent benign pain, which can be aggravated by anti-cancer treatment or cancer progression, such as disc prolapse, osteophytes, osteoarthritis, rheumatism, rheumatoid, migraine and so on. Early diagnosis and early treatment should not neglect the control of accompanying pain while actively treating cancer, especially when cancer cannot be cured and pain has become the main pain, cancer pain should be actively treated to alleviate the pain of patients, maintain the personality of cancer patients and improve the quality of life of cancer patients. Here we recommend a method to alleviate cancer pain by combining Chinese and Western medicine, which can bring pleasure to cancer patients. 80 grams of white peony, 30 grams of roasted licorice and 200 ml of cool water in a casserole soaked for 3 hours, first decocted with rapid fire until boiling and then changed to a gentle fire to decoct for 20 minutes, filtered out the liquid and then add 200 ml of cool water soaked for 30 minutes to decoct for 20 minutes with a gentle fire, then filtered out the liquid and then add 200 ml of cool water soaked for 30 minutes to decoct for 20 minutes with a gentle fire and filtered out the liquid. The three times filtered liquid was poured together and divided into four portions, and 1/4 portion was taken twice a day. 20% mannitol 250 ml was intravenously dripped within 60 minutes to 90 minutes, once a day. The original formula of white peony and roasted licorice is “Paeonia lactiflora and licorice soup”, which originated from Zhang Zhongjing’s “Treatise on Typhoid Fever – The Sun”, and “Symptom Causes and Pulse Treatments – Volume 4” is called “Wuji Tang”, which is effective in regulating the liver and the spleen, easing the urgency of the situation and relieving pain. Nowadays, it is widely used in the treatment of gastrocnemius muscle spasm, intercostal neuralgia, stomach spasm, gastric pain, abdominal pain, sciatica, gynecological inflammatory abdominal pain, dysmenorrhea, and duodenal ulcer caused by blood deficiency and fluid injury. According to modern pharmacological research found that peony has a central analgesic and inhibit spinal reflexes; licorice has a sedative and inhibit peripheral nerve effects. According to experimental and clinical observation, only when peony and licorice are used in larger dosages and in a certain proportion can they exert the best pain-relieving effect. Mannitol is a kind of dehydrating agent. Intravenous drip can not only dehydrate the cancer cells to slow down their metabolism and growth, reduce the tumor body to reduce the pressure on the surrounding tissues, but also act as an oxygen radical scavenger to remove the high free radicals in the tumor body. Observed mannitol in 60 minutes to 90 minutes time intravenous drip will not occur dehydration of the adverse performance, as long as a little more drinking water can be. This method of suffering from cancer pain friends may try, the effect can be known.