Pain is a common symptom in patients with tumors, and cancer pain is present in about a quarter of newly diagnosed cancer patients, a third of those undergoing treatment, and three-quarters of those with advanced cancer. Cancer pain is one of the symptoms that most affects patients’ quality of life. According to Chinese medicine theory, cancer pain can be divided into yin and yang evidence. Clinical observation shows that cancer pain is predominantly yin evidence, and yin evidence of cancer pain is mainly manifested as localized skin swelling, or nodular masses, while the color of the skin remains unchanged, and the painful part likes warmth, such as adding a warm water bag for more comfort, and the pain can be alleviated by massaging the painful part, and patients are afraid of cold as the main manifestation. Chinese medicine believes that the cause of pain in these patients is mainly due to the cold evil cohesion in the painful parts, resulting in this part of the qi and blood does not pass, the meridians are not smooth, qi and blood can not be glorified is painful. Patients with Yang syndrome have redness, swelling, burning and pain in the painful area. For patients with Yang syndrome, the treatment of clearing heat and removing toxins and cooling blood should be taken to treat the pain, while for patients with Yin syndrome, the treatment of warming Yang and dispersing cold, removing toxins and dispersing nodules, and clearing the channels to alleviate pain should be taken to warm the meridians and clear the channels, and the Yang qi can push the operation of qi and blood in the meridians to dissolve the localized cold condensation, stagnation and stasis in the painful area, and then through the use of phlegm-softening, softening, detoxification drugs to make the localized nodules to be dissolved. The localized nodules can be softened and dispersed by detoxifying medicines, so that the poisonous evils can be dissolved, thus achieving the efficacy of pain relief, and the localized external application of medicines can make the medicines reach the place of disease directly and produce better curative effects. For the yin evidence of pain, to ginger and pain relief cream external efficacy. Among them, dry ginger, fine Xin, Radix Angelicae Sinensis warms Yang and disperses cold to warm and pass the pain, whole scorpion passes the pain, dried toad skin detoxifies and relieves pain, raw Semixia, Zhebeimu dissolves phlegm and disperses knots, white peony and roasted licorice form Peony and Licorice Soup to ease the pain and relieve the pain, clove has a pungent odor to go away and can lead the medicines through the skin to the place of disease, the use of ginger juice can enhance the therapeutic efficacy of warming and passing the pain and the smell of ginger and ginger juice is pungent and fragrant, and together with the clove, they play a role of drawing medicines to the inside of the patient’s body. Ginger and ginger juice have a pungent odor, and together with cloves, they can lead the medicine into the interior. For patients with sensitive skin, honey can be used to harmonize the herbs, as it protects the skin and has detoxifying effects. The combination of all the medicines can produce better pain relief, and the clinical side effects are slight. Some patients do not want to apply drugs externally, you can also use cotton cloth sewn into a bag, filled with the above drugs, placed in the pain localization, can also play a very good pain effect, and more convenient to use, the patient can be used 24 hours. The prescription can be added or subtracted with the evidence, easy to use. This method is safe, effective, convenient and easy to implement, without obvious toxic side effects, and is worthy of further promotion.