The neck of the foot mainly refers to the ankle area clinically. Unilateral ankle pain may be caused by a variety of factors, such as muscle strain caused by exertion or exercise in daily life, trauma caused by violence, inflammation and tumor of the ankle joint, etc. In addition, abnormal blood circulation in the ankle joint can also lead to joint damage. Therefore, patients need to clarify the cause of pain and then treat it symptomatically: 1. Muscle strain: If overexertion in daily life or strenuous exercise causes chronic strain on one side of the muscle, it can lead to pain in the unilateral ankle. This can be improved by adjusting the lifestyle, paying attention to rest, reducing weight-bearing and strenuous activities of the ankle joint, and increasing measures to prevent cold and keep warm. 2. Trauma: violent acts such as impact and stretching of the unilateral ankle can cause acute damage to the soft tissue of the unilateral ankle, resulting in swelling and pain symptoms. If the pain is obvious, you can take ibuprofen extended-release capsules, aspirin and other non-steroidal anti-inflammatory drugs orally under the guidance of a doctor; 3, ankle inflammation: such as rheumatoid arthritis, gouty arthritis, synovitis, tendonitis, etc., can show the symptoms of pain at the unilateral ankle, at this time, the original disease should be actively treated; 4, ankle tumor or tuberculosis: tumor invading the surrounding tissues of the unilateral ankle can damage the bone, and then show as 5.Ankle circulation abnormalities: such as vasculitis, varicose veins, etc., can lead to local venous blood flow obstruction in the unilateral ankle, resulting in blood stagnation, manifesting as swelling and pain.