The cause of chest tightness, shortness of breath and coughing at night must be clarified by improving the corresponding tests. First of all, we should rule out the presence of bronchial asthma. Patients with bronchial asthma are more likely to have a good onset of clinical symptoms at night, mostly due to vagal excitation, which leads to a significant increase in airway hyperresponsiveness and bronchospasm, and manifests as chest tightness, shortness of breath and cough. After the diagnosis is clear, inhaled glucocorticoids and bronchodilators should be administered. Secondly, it is necessary to exclude any cardiac disease. The increase in the amount of returning blood at night when sleeping increases the burden of cardiac function, and patients with heart failure tend to have symptoms of chest tightness, shortness of breath and cough.