Jerking off may lead to glansitis. Glansitis is an inflammation caused by infection, trauma and other stimuli, mostly with redness, erosion and ulceration as the main clinical manifestations. When a man jerks off, he doesn’t pay attention to hand hygiene and cleanliness or the presence of bacteria on his hands, and jerks off in an excessively rough position, too hard, it will lead to local skin breakage of the glans, so that bacteria invade through the injury trauma and cause infection, which leads to glansitis. In addition, long-term excessive frequent masturbation, jerking off, will make the glans become sensitive, and their own immunity will also decline, which leads to bacteria more easily invaded.