Leg weakness caused by diabetes may be caused by muscle atrophy, or it may be caused by complications such as diabetic peripheral neuropathy, hypoglycemia, etc. All of them need targeted treatment under the guidance of doctors, such as hypoglycemic treatment, nutritional nerve treatment, sugar supplementation treatment, etc. 1. Hypoglycemic treatment: If the patient’s long-term blood sugar control is not good, the absorption and utilization of sugar is impaired, resulting in excessive consumption of fat and protein in the muscle, and the muscle atrophy of the lower limbs, which will lead to weakness of the legs. It is necessary to take oral hypoglycemic drugs such as metformin or insulin injection as prescribed by the doctor, together with diet control and appropriate exercise. 2. Diabetic peripheral neuropathy: Treatment for peripheral neuropathy on the basis of blood glucose control, including nutritive nerve and vascular protection treatment. 3. Hypoglycemia: when diet or hypoglycemic drugs are used improperly, it may lead to hypoglycemic reaction, which may also be manifested as leg weakness, sugar water or sugary food should be given in time, and it is recommended to consult a doctor for intravenous rehydration of sugar in time if the symptoms don’t get better or aggravate significantly. If the symptoms do not improve or worsen significantly, it is recommended that diabetic patients go to the hospital for treatment.