1, diet diet needs to be diversified, nutrition needs to be properly matched, more multivitamins and fruits. “Three high and one more”, that is, high calorie, high protein, high fiber, and more water. The intake of high-calorie food can ensure the basic physiological needs of the body and maintain the weight at a normal level; the intake of high-protein food can ensure the repair of the skin and hair after suffering from chemotherapy damage. Nutritionists believe that the protein required by patients during chemotherapy should be increased by 50%, the calories required by 20% and the water required by 50% compared with the general situation. Three should not be: ① should not drink more water when eating, preferably 1 h before and after the meal. ②Eating speed should not be too fast, to chew fully, so that the food is fully digested. ③It is not advisable to lie down immediately within 2 hours after a meal, and it is better to rest on a chair for a period of time. During chemotherapy, patients should drink more water than usual to ensure normal kidney function and metabolism and excretion of drugs. If the daily urine volume is less than 1,500 mL, it often indicates that not enough water is being drunk, and supplemental water can be chosen flexibly. But do not drink drinks containing ethanol, because ethanol may interact with some drugs to reduce the efficacy or serious consequences. 2, gastrointestinal reactions loss of appetite in the first of the gastrointestinal symptoms. Reduced food intake leads to a negative nitrogen balance, and the patient’s immunity is reduced, causing or aggravating infections. Change the cooking method frequently, pay attention to the color, aroma and taste to increase the patient’s appetite, mainly light food, avoid thick condiments and fried, greasy food. And encourage patients to do appropriate activities or use a little appetizing food, drinks, such as sour plum soup, juice, etc. before eating, and if necessary, give digestive drugs to increase appetite and promote diet. Nausea, vomiting nausea, vomiting in the digestive tract reactions take second place, not only directly affect the patient’s quality of life, but also affect the smooth implementation of chemotherapy, in serious cases can lead to dehydration, electrolyte imbalance, weight loss, and even failure. It is recommended that patients should avoid eating 2h before chemotherapy, and after the nausea and vomiting are relieved at the end of chemotherapy, they should eat a small number of meals, each meal should not cause vomiting, drink more water, give mild and non-irritating food, avoid too sweet, greasy, or too cold, too hot, spicy stimulating food. Limit bananas, walnuts, eggplant and other foods, and reduce the intake of tryptophan-containing protein. Patients should avoid foods and beverages that are too hot, acidic, rough, hard, and irritating, such as coffee. Food and beverages should be at room temperature when eating, and food should be steamed in an autoclave in order to sterilize and keep the food clean and sterile to the maximum. Brush your teeth with a soft-bristled toothbrush or rinse your mouth with warm water or mouthwash after eating to remove food debris and keep your mouth clean. For severe pain, add 2% lidocaine to the gargle for pain relief. Diarrhea Provide foods with low fiber content to diarrhea patients and avoid excessive fats, fried or too sweet foods. While applying antidiarrheal drugs, try to exclude foods that may cause diarrhea. For severe diarrhea, give a diet of boiled millet soup, which has a good tonic function for the stomach and intestines, and pay attention to water and electrolyte supplementation, using more foods with high potassium content, such as vegetable soup, orange juice, tomato juice, etc., to replenish potassium. Common 5-FU can cause intestinal mucosal damage leading to abdominal pain and diarrhea. Daily consumption of yogurt can replenish gram-negative bacilli killed by 5-FU and reduce symptoms. Patients with constipation are hospitalized for chemotherapy and spend more time in bed. Gastrointestinal peristalsis slows down, appetite decreases, food and water intake decreases, and intestinal contents are insufficient to stimulate normal peristalsis; due to chemotherapy, especially the application of certain antiemetic drugs, intestinal peristalsis slows down, leading to constipation. Constipated patients are prone to anal fissures, and the anti-infection ability of tumor patients obviously decreases after chemotherapy, once anal fissures occur, it is easy to cause perianal infections, and in serious cases, bacteria or local breakage into the blood leads to bacteraemia and other serious situations, which not only increases the pain of patients, but also brings great influence to the treatment. Patients should eat more vegetables and fruits. Because dietary fiber is a carbohydrate in food that cannot be absorbed directly. Dietary fiber can combine with bile acids to reduce the concentration of other carcinogenic substances, relieve the effect on intestinal mucosa, promote intestinal peristalsis, and excrete the contents, so consuming dietary fiber can relieve patients’ indigestion and constipation. Yogurt can effectively help digestion and reduce the symptoms of indigestion, nausea, vomiting and constipation caused by chemotherapy drugs. Yogurt can stimulate gastric acid secretion, increase gastrointestinal digestive function and promote metabolism. Drink more water or juice, eat more radish, garlic, jam, raw cucumber and other foods to increase intestinal peristalsis. Add some fatty foods such as peanuts, walnuts sesame and soybean oil, etc. Patients can also be encouraged to exercise appropriately and develop good bowel habits. Most of the cancer patients have pessimistic and depressive moods. Not only do they have to bear the discomfort brought by the disease treatment, but also have to bear different degrees of psychological and social pressure, patients often have anxiety, fear, depression, pessimism and other psychological reactions. These negative emotions will seriously affect the quality of life of patients. Patients should be introduced to the hospital environment and ward facilities in detail, eliminate the sense of unfamiliarity, understand the patient’s state of mind in a timely manner, actively channel them, often talk to patients on weekdays, implement touching services, warm services and comfortable care while providing physical care to patients, gain patients’ trust, inform them of the possible adverse reactions after chemotherapy, try to eliminate their concerns, make patients relax, maintain optimism and build up The patient can relax, maintain optimism and build up confidence to overcome the disease. Basic care to create a comfortable environment, keep the ward clean, fresh air, no odor, vomit timely clean up, reduce adverse stimulation. Give assistance to patients when they vomit, such as rinsing their mouths, cleaning their faces, changing clean clothes, arranging bed sheets, assisting patients to take comfortable positions, and ensuring adequate rest and sleep. Health education is aimed at the patients’ lack of knowledge about chemotherapy, explaining patiently the purpose and method of chemotherapy and the possible side effects of treatment, so that patients can correctly understand and treat chemotherapy, actively cooperate with chemotherapy and increase their confidence in overcoming the disease. However, it should also be noted that health education should be tailored to the individual and proportional to avoid counterproductive effects.