Wang is a department manager of a joint venture, 33 years old, usually healthy. One evening while reading a book, he suddenly felt palpitations, chest tightness, chest pain, chest pressure, dyspnea, accompanied by an obvious sense of suffocation and near-death feeling, while showing a pale face and sweating profusely. He was immediately taken to the emergency room of a large hospital. Considered as “angina attack”, after oxygen, cardiac monitoring, cardiac protection, coronary artery dilation, sedation and other treatments, the condition completely relieved after half an hour. However, when he returned home that night, the above symptoms recurred and were relieved after another resuscitation. Subsequently, there were many intermittent episodes, each time to send to the emergency room for rescue. Manager Wang then spent nearly 10,000 yuan to do a variety of related tests, but no obvious pathological changes were found, even the blood lipid level is also in the normal range. What kind of disease is he suffering from? Though he had consulted many doctors, he was still unable to get any results. Finally, he was diagnosed in the psychiatric department, and it turned out that he suffered from a type of anxiety disorder: panic disorder. After nearly half a year of systematic psychotherapy combined with medication, his condition has stabilized, and he has not experienced any similar attacks. Anxiety disorder, also known as anxiety neurosis, is a neurological disorder characterized by widespread and persistent anxiety or recurrent panic attacks. It is categorized into two types: generalized anxiety and panic disorder, and its onset is often related to certain psychosocial factors. Generalized anxiety is characterized by frequent or persistent tension without a clear object or fixed content, or excessive worry or annoyance about certain problems in real life. This kind of tension, worry or annoyance, and the reality is very disproportionate, so that the patient feels unbearable, but can not get rid of. The content or object of the patient’s worry is mostly unclear, but it may also be the worry about one or two non-realistic threats or unfortunate events in life that may happen to him or his friends or relatives, such as repeated worry that a loved one will get into a car accident when he goes out. Generalized anxiety is often accompanied by vegetative hyperfunction, such as palpitations, shortness of breath, choking sensation, dizziness, excessive sweating, dry mouth, and even sexual dysfunction. It can also manifest motor restlessness, such as rubbing hands and feet, walking back and forth, not being able to sit still, muscle tremor, etc. At the same time, there is over-vigilance, easy to frighten, easy to provoke, difficulty in falling asleep, easy to wake up and other symptoms. Panic disorder, also known as panic disorder, is an acute anxiety disorder characterized by recurrent significant palpitations, sweating, tremor and other vegetative symptoms, accompanied by a strong sense of near death or a sense of loss of control, and fear of unfortunate consequences of panic attacks. Typical manifestations are the sudden emergence of a strong sense of fear when the patient is engaged in daily activities, such as reading a book or eating a meal, as if he is about to die or will lose his mind, as well as palpitations, as if his heart is about to jump out of his mouth, chest tightness, chest pain, chest pressure or dyspnea, throat blockage, as if he can’t breathe. Some experience dizziness, excessive sweating, facial flushing or paleness, numbness of the hands and feet, gastrointestinal discomfort and other vegetative symptoms. The attack usually lasts 5-20 minutes, rarely more than an hour, and resolves on its own. Because many of the symptoms of panic disorder are similar to certain cardiovascular and respiratory diseases, patients with first-episode illnesses tend to be seen in the emergency department, which is highly susceptible to misdiagnosis. These patients should go to a mental health professional as soon as possible after exclusion of organic diseases to avoid delayed treatment and unnecessary economic burden. The treatment of anxiety disorders is mainly based on systematic psychotherapy combined with medication. Psychotherapy treatment includes supportive psychotherapy, relaxation therapy (such as biofeedback therapy), cognitive behavioral therapy, hypnotherapy and so on. Commonly used therapeutic drugs include benzodiazepines (e.g., alprazolam, clonazepam, diazepam, lorazepam), beta-blockers (e.g., cardiac glycosides), and some antidepressants (e.g., paroxetine, fluoxetine, sertraline, citalopram, fluvoxamine, venlafaxine, mirtazapine, etc.).