The correct use of chemotherapy can control the tumor and prolong the survival of patients. However, there is a tendency to abuse chemotherapy in clinical practice. Some patients who have undergone repeated chemotherapy end up with tumor not only not controlled but also physically victimized. In some cases, although the tumor is temporarily controlled, the survival time is not prolonged but shortened because the body is weakened. Combining personal experience and expert consensus, we would like to introduce some strategic thinking about cancer chemotherapy to our patients and friends for reference only: 1. The overall efficiency of chemotherapy for cancer is about 30%, and even if it is effective, the maintenance time is only two to three months, after which the growth is accelerated. Patients can’t afford to be hurt by continuous chemotherapy, which is costly and ineffective. Although we are dissatisfied, these are the basic facts. It is also based on such challenges that prompt us to explore, improve and enhance the effectiveness of chemotherapy. 2. It is impractical to cure cancer, and it is the purpose for patients to live well and live long. That is, advanced cancer is almost impossible to be cured, and we must accept this fact, adjust our mentality, and not simply chemotherapy because of the delusion of cure, let alone excessive chemotherapy. Chemotherapy is not an end, but only a means. People-oriented, the patient lives well and long is the goal. If chemotherapy can not achieve this purpose, do not also, must not be forced. 3.Post-operative chemotherapy should be indicated and gentle. After tumor surgery, not all need chemotherapy, chemotherapy needs prerequisites, otherwise it is harmful and unhelpful. What are the conditions? The general conditions are: the body must be good, high malignancy, large tumor, lymph node metastasis, local invasion, in addition, the disease should be relatively sensitive to chemotherapy to be allowed. For example, kidney cancer, colon cancer and melanoma are not sensitive to chemotherapy, and chemotherapy is usually not needed after surgery for early to mid-stage colon cancer. Even if chemotherapy is needed, it should be as gentle as possible, why? Because after the tumor is removed, the efficacy or even ineffectiveness is not visible, and the toxicity of chemotherapy is high, so it should be stopped when it is appropriate. 4. Late chemotherapy should be seen while chemotherapy is being administered, and the replacement plan should be careful. There is a characteristic of chemotherapy for advanced recurrent tumor, which can be seen in the tumor. If there is no effect, it will be seen after two times of chemotherapy and CT review. What if the tumor does not get smaller? The conventional practice is to change the chemotherapy regimen, but we do not agree with it. However, we don’t agree with this because the efficiency of the change of regimen will be lower, the toxicity will be higher, and the patient will not get the benefit basically. So what to do? Western medicine rarely has a good solution. Only Chinese medicine or a combination of Chinese and Western medicine can improve the efficiency and at least the toxicity will be minimal. If the tumor shrinks significantly, you can consider to continue chemotherapy for 2 times. It is not advisable to do too much, because the effect of continuing chemotherapy will definitely get worse and worse, and the toxicity reaction will get bigger and bigger. 5. The standard is not necessarily the best, but the patient is the center. Each patient’s degree of illness, physical fitness, psychological state are different, treatment should be different from person to person, rather than chemotherapy into a formula, the patient hospitalized like a rush, rush a cut, five days seven days whisked away from the hospital. The chemotherapy protocols and doses in the book are standardized, but they are not set in stone. Some doctors all for the dose standard and the completion of the chemotherapy course, do not hesitate to play raw white needle, do not hesitate to rush time to catch up, the patient around the chemotherapy turn, rather than chemotherapy around the patient set, the results are imaginable. 6, emphasizing the comprehensive treatment, to take advantage of all the strengths, rather than should be arbitrarily rejected. There is no single means to control cancer, especially for advanced cancer, comprehensive treatment, taking advantage of the strengths and avoiding the weaknesses, is the main idea. During the treatment of chemotherapy, the cooperation of Chinese medicine is very important! After surgery, long-term anti-relapse treatment with TCM is very important! The reasoning is not much elaborated.