Herpes pearls often occurs in young people and adults, usually between the ages of 20 and 40. 35% of normal people will have it, mostly in young people who are circumcised and have masturbation habits. It is a physiological abnormality and is not a sexually transmitted disease. It may be related to the long foreskin, more circumcision, resulting in chronic inflammatory stimulation. Examination and treatment of pearl papules are negative for human papillomavirus by polymorphism chain reaction, and thus are not sexually transmitted diseases. It can be differentiated from condyloma acuminata by clinical, histopathological and human papillomavirus examinations and is not difficult to diagnose. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. 1, laser therapy (hospital equipment treatment) Advantages: laser therapy is a high-temperature treatment, the temperature can reach 700 ℃ or more. It mainly makes the pearl rash tissue charred and crusted, and after the scabs fall off, the trauma is covered by newborn squamous epithelium. Treatment of pearlescent rash generally uses a carbon dioxide laser with an infrared light wavelength of 10.6 μm. The preparation prior to treatment is the same as for electrolysis. The advantages of its thermal effect, in addition to pressure, photochemical and electromagnetic field effects, so in the treatment of anti-inflammatory (to stimulate the body to produce a strong defense immune function), pain relief (so that the tissue edema subside, reduce the chemical and mechanical stimulation of nerve endings) and promote tissue repair (to enhance the anabolic effect of epithelial cells, promote epithelial proliferation, accelerate wound repair), so the treatment time is short, high cure rate. Disadvantages: higher cost, high price of imported laser equipment, so the price of removing pearl rash is also higher and easy to recur. After surgery, you need to change the medication regularly to avoid infection until full recovery. 2, cryotherapy (hospital equipment treatment) Advantages: cryotherapy is an ultra-low temperature treatment refrigeration source for liquid nitrogen, the temperature of -196 ℃. Treatment according to the pearl rash situation to choose the appropriate probe. To improve the effectiveness of the treatment can be used freeze-soluble-freezing method, that is, freezing for 1 minute, rewarming for 3 minutes, and then freezing for 1 minute. The advantage is that it is simple to operate. Disadvantages: The disadvantage is that the liquid nitrogen spray is gas, the area is difficult to control, easy to blister after freezing, easy to infect and scarring. The popularity is not as good as laser therapy. 3, drug treatment Advantages: pearl gram role pearl rash accelerated growth necrosis and fall off, the process is easy because it is used externally, no side effects, not easy to recur, etc.. Disadvantages: the treatment takes 3-10 days, and the point of medicine 24 hours can not touch water or affect the effect. In conclusion: patients should maintain good habits and quit SY to prevent recurrence.