Candida glans is a fungal disease of the mucous membrane of the skin caused by the conditional pathogenic fungus Candida albicans, which mostly develops when the systemic or local resistance is reduced (excluding whether the patient has diabetes), often from spousal infection, with a high prevalence in those who are circumcised or circumcised, and is prone to recurrence. In the past two years, we have performed circumcision on patients with recurrent Candida glans after antifungal treatment with satisfactory results. The treatment method: 250mg/d of orally administered lamisil tablets, topical application of furnace glycolic lotion, circumcision after the disappearance of clinical symptoms, cases are evaluated 3 weeks after the end of treatment, 3 months, 6 months, one year follow-up follow-up, observation of clinical recurrence, avoid alcohol, spicy things and sexual life during treatment, the patient’s sexual partners also need to be treated and followed up at the same time. The most common cause is Candida, the majority of patients often have physiological prepuce or circumcision, and after sexual maturity, sebaceous glands secrete a lot and mechanical damage. The skin sensitivity increases, plus the closed, moist physiological environment, making it easier for foreskin scale to accumulate and difficult to discharge, while the foreskin scale is suitable for the growth and reproduction of Candida, and provides a more favorable parasitic site for its repeated attacks, making it more difficult to treat. After excision of the long foreskin, the skin inside the foreskin cavity remains dry, which reduces the stimulation of the foreskin scale and destroys the living environment of Candida, thus inhibiting the chance of reinvasion and cross-infection of Candida and significantly reducing the recurrence rate. Due to the long course of preventive medication and treatment with fluconazole in recent years, which leads to a large number of irregular use of azole drugs, the resistance of Candida to them increases, so the sensitivity of fungal diseases to azole drugs gradually decreases, and the treatment effect is poor and recurrent. Terbinol belongs to arylamine derivatives, which can inhibit fungal squalene epoxidase, causing excessive accumulation of squalene and blocked synthesis of ergosterol in fungal cells, resulting in defective fungal cell membranes, thus playing a fungicidal or antibacterial role, and also reducing the ability of Candida albicans to produce reactive oxygen clusters (ROS). In this study, the cure rate of recurrent candidal glansitis treated with circumcision combined with lamisil was 87.1% at 3 weeks of treatment, respectively. The patients had significantly lower clinical recurrence rates at 3 months, 6 months, and 1 year after treatment, as well as a significant decrease in recurrence rates among sexual partners, presumably because of the decreased incidence of glansitis in male patients after circumcision. Therefore circumcision plays a positive barrier role in stopping recurrent Candida infections, and the long-term efficacy is more significant than the recent efficacy, which is permanent, while medication is transient and cannot be relied on for long-term medication to prevent the occurrence of the disease, as such drug-resistant strains have long appeared. In conclusion, the clinical efficacy of circumcision combined with lamisil in the treatment of recurrent Candida glans foreskinitis is clear and has clinical promotion value.