Demyelinating changes in the white matter of the brain are nerve cell demyelination in response to noxious stimuli. Nonspecific demyelinating changes are common in normal people and do not require treatment. Specific demyelinating changes caused by common diseases need to be examined according to the symptoms, such as blood tests, lumbar puncture examination, and complete neurological physical examination, to determine the cause of the disease, and then carry out the treatment for the cause. I. Non-specific demyelinating changes Occasionally, scattered demyelinating changes are found in the form of dots and patches, which are called non-specific demyelinating changes and do not require treatment. Second, specific demyelination changes 1, multiple sclerosis: cerebral white matter demyelination changes can be caused by multiple sclerosis, multiple sclerosis is a neurological autoimmune disease, need to give hormones, immunosuppressants, monoclonal antibodies or interferon and other drugs for treatment; 2, dysplasia: caused by congenital, hereditary, progressive cerebral white matter dysplasia disease in children, caused by genetic variations. There is no treatment; 3, cerebrovascular disease: cerebral white matter demyelination changes may also be due to abnormal vascular development caused by cerebrovascular disease. Usually due to genetic changes, there is no eradication of the treatment, only for the symptoms of cerebrovascular disease for conventional treatment, such as anti-platelet aggregation therapy, lipid-lowering therapy, control of blood pressure therapy or improve microcirculation therapy.