Rheumatoid arthritis is a chronic, predominantly inflammatory synovitis systemic disease of unknown etiology. Its most unbearable for patients and friends is the obvious pain, and this is what patients want to solve most! But in fact, rheumatoid arthritis is not only painful and upsetting, the most frightening thing is that it gradually causes joint deformation and reduced joint mobility, leading to a decline in the patient’s somatic functions and even eventually causing inability to care for oneself, paralysis and death. A qualified rheumatologist should not only solve the “symptoms” of joint pain, but also try to delay the “root” of joint deformation. The purpose of rheumatoid arthritis treatment is mainly to relieve pain, these drugs work fast, generally after taking can quickly relieve pain, the representative drugs are anti-inflammatory drugs: such as etoricoxib (Ankangxin), Celebrex (Celebrex West), meloxicam (Hongqiang, Mobic), diclofenac (Intacrine, Fotalin); or hormones: such as prednisone, methylprednisolone, Depo Pine and so on. But these drugs can only relieve the pain, not to delay the joint condition. Therefore, in the treatment of rheumatoid arthritis, these drugs only play the role of the “advance team”, generally the latter “cure” drugs once the effect, these drugs will be slowly withdrawn, until discontinued. It must be stressed that it is not reasonable to treat rheumatoid arthritis with such drugs alone – after all, it is only treating the symptoms, not the root cause! The ultimate goal of rheumatoid arthritis treatment is to control the disease, both: not only to relieve the pain, but also to delay the deformation of the joints. These drugs are called “disease-controlling drugs” by the rheumatology department, also known as “slow-acting drugs”, representing drugs such as: methotrexate, leflunomide, elamodil, and raglan polysaccharide. These drugs can slow down the deformation of the joints and really achieve the effect of “disease control”. But unfortunately, the effect of these drugs is slow, often need to take 1-3 after the effect, that is to say, from the start of the drug to the drug takes 1-3 months to take effect, so before the effect of these drugs, the need to take the symptoms of the drug is not difficult to understand. However, these “curative” drugs are the “main force” in the treatment of rheumatoid arthritis, and are also the most difficult to weigh in the treatment of rheumatoid rheumatism, must be evaluated by a rheumatologist to adjust the use of these drugs, patients can not arbitrarily add or subtract these drugs Patients cannot add or subtract these drugs at will. So we must now have a doubt, there is no one drug can “treat both the symptoms and the root cause” it. In fact, there is, that is, biological agents biological agents not only fast-acting, can play a certain anti-inflammatory and analgesic effect; also can really control the disease, delay the joint deformation. But unfortunately, these drugs tend to be more expensive, and are generally used for patients with heavy disease, or poor control of traditional drugs, not everyone needs to use. Therefore, rheumatoid arthritis treatment requires a combination of treatment of the symptoms + the root cause, but the specific choice of medication needs to be made according to each individual’s condition. This work needs to be carried out by our rheumatologists. Patients must follow the instructions of their rheumatologists to carry out medication and not adjust the medication on their own.