Chronic glomerulonephritis pathological damage, mostly proliferative and sclerotic lesions, in clinical hypercoagulable state, so it can be inferred that chronic nephritis from the beginning to the end of the existence of blood stasis. Therefore, the method of activating blood stasis has become the main therapy for chronic nephritis. The characteristics of Chinese medicine to improve blood rheology are firstly, effective, and secondly, less toxic side effects, which can be used for a long time. Such Chinese medicines include: Salvia, Panax ginseng, Phellodendron, Peach kernel, Safflower, Red peony, Mao Dongqing, Angelica, etc. Small doses of leeches (3-6g) can also play a good role in the treatment. In nephrotic syndrome, the tendency of coagulation and thrombosis is more serious in this disease because of the increase of synthetic fibrinogen and V, VIII, VIII and X coagulation factors in the liver, coupled with low protein and hyperlipidemia also causing blood concentration and increased blood viscosity. Chinese herbs such as Chuanxiong, Angelica, Radix Paeoniae, Safflower, Yimoucao, Danshen, Mao Dongqing, leech, Dilong, pit viper, blood exhaustion, curcuma, peony bark, peach kernel, mullein, clove, ocimum sanctum, cinnamon stick, etc., have anticoagulant and antithrombotic effects. Some of the dialysis patients with chronic renal failure may have hyperviscosity, so that the dialysis process is prone to dialyzer blockage, which reduces the effectiveness of dialysis, reduces the number of dialyzer reuse, and increases the economic burden of dialysis patients. Some patients even have thrombosis of important organs as a result. Increasing the dosage of heparin can improve the hyperviscosity of blood, but excessive use of heparin can increase the activity of lipoproteinolytic enzymes and promote the decomposition of fat, resulting in elevated free fatty acids in the blood and low cellular immune function, leading to an increased incidence of infection. In addition, heparin may activate complement, causing a decrease in leukocytes, an increase in C3, and a decrease in arterial partial pressure of oxygen. Therefore, minimizing the dosage of heparin during dialysis still has positive significance. Long-term oral administration of Danshen, Tianqi and their preparations, dialysis with Danshen injection or Chuanxiongzin, hemosiderin, etc. added to GS intravenously; or the addition of Tianqi or Danshen to stew is beneficial to reduce blood viscosity, decrease the dosage of heparin and increase the number of dialyzer use.