Patient Question:Disease:Shadows in the lungsDescription:The cough started in x months of 20xx and has lasted for about x months with chest pain, no fever, normal temperature, no improvement, and a radiograph showed shadows in the lungs, and the doctor suggested puncture for further examination. The sputum test did not find antacid bacillus, thoracic surgery department of Xuanwu Hospital of Capital Medical University Su Lei would like to provide help:Please ask the doctor: is it necessary to do a puncture to confirm the diagnosis? Is it more likely that our case is a tumor? I heard that there are some risks associated with puncture. The family is very anxious. Can you give us some better advice? Reply from Su Lei, Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University Lung Cancer Treatment Center: From the uploaded photos, it does not look like tuberculosis. Not all lung lesions need to be punctured. However, in view of the uploaded imaging data and description of the disease, puncture is very necessary. Puncture is the direct pathological diagnosis and the gold standard for diagnosis. In addition, serum tumor marker test can be beneficial to determine. Patient question: Dr. Su, thank you for your reply. The patient has been diagnosed with advanced lung cancer through puncture. We are very sad. The attending doctor said that chemotherapy treatment is needed, but after checking a lot of information, it is said that chemotherapy has a lot of side effects. Do you have any better advice? Thank you so much! Reply from Su Lei, Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University Lung Cancer Treatment Center: From the above CT photo, the lesion is located in the periphery of the upper lobe of the left lung. If possible, visit the outpatient clinic and bring your medical records.