Burning sensation in the chest mostly belongs to digestive tract diseases such as gastritis, ulcer, gastroesophageal reflux disease, esophagitis, etc. In addition, stomach cancer and esophageal cancer need to be excluded. In normal people, burning sensation in the chest is most often caused by eating spicy and stimulating food or alcohol, or sometimes by bending down after a full meal, which leads to acid reflux, or occasionally by bile reflux due to gallbladder or gastrointestinal contraction, or by mistakenly taking other acidic or alkaline substances, which can cause burning sensation in the chest due to stimulation of the gastroesophageal mucosa. After ruling out these occasional cases, it is necessary to consider whether they occur frequently. If the burning sensation in the chest occurs frequently under normal eating conditions, it is necessary to consider gastritis, esophagitis, gastric cancer, esophageal cancer, gastric ulcer, esophageal ulcer, etc. In order to make a clear diagnosis, relevant examinations such as gastroscopy and pathological biopsy if necessary should be performed. After excluding the symptoms of irritation of gastroesophageal mucosa caused by spicy and irritating food, alcohol consumption, acid and alkaline substances, we should consider whether there are digestive tract diseases such as inflammation, ulcers, malignant diseases, etc.