1, what is the cause of vitiligo?
The incidence of vitiligo is about 0.1% to 2%, there is no gender difference, the incidence is higher in the dark skinned population than the light skinned. The exact cause is not clear, but it is closely related to genetics, autoimmune defects, neuroendocrine disorders, melanocyte self-destruction and biochemical abnormalities.
2, what kind of performance does vitiligo have?
The actual fact is that you will be able to find out more about the actual actual actuality.
4, vitiligo patients understand common sense
(1) Vitiligo patients have a certain heredity, but will not necessarily inherit to the next generation.
(2) Vitiligo is not contagious.
(3) Vitiligo is not easy to cure, but completely possible to cure.
(4) Vitiligo has no so-called radical cure package therapy.
(5) Vitiligo needs to choose different therapies according to different types.
5, what is the best treatment for vitiligo?
The actual fact is that there is no special cure for all the different types of vitiligo, but with the development of modern medicine, many advanced vitiligo treatment methods are constantly appearing, currently the commonly used vitiligo treatment methods include photochemotherapy (PUVA therapy), phototherapy (narrow wave UVB therapy, 308 nm excimer laser, 304 nm high energy ultraviolet therapy), nitrogen mustard ethanol, surgical therapy (autologous epidermal transplantation method, melanocyte culture transplantation method, skin grinding + 5-fluorouracil cream therapy, etc.), topical hormone cream, immunomodulator tacrolimus ointment, pimecrolimus ointment, etc., herbal therapy, tattoo color method, depigmentation method for vitiligo. According to the patient’s different conditions to formulate individualized treatment plan is the best choice for both doctors and patients.
6, vitiligo will inherit to the next generation?
The actual fact is that you will find a lot of people who are not able to get a good deal on a lot of things. The actual fact is that you will be able to get a lot more than just a few of the most popular and also the most popular. The heritability of primary hypertension is 62%, peptic ulcer is 37%, coronary heart disease is 65%, diabetes is 75%, bronchial asthma is 80%, compared to the heritability of vitiligo is not only very low, and in the clinical family history of vitiligo patients only account for a very small percentage.
7, how to treat the progressive vitiligo?
The localized or segmental vitiligo can be treated with topical glucocorticoids or other immunomodulators, immunomodulators (transfer factor, thymidine, etc.), local phototherapy: narrow frequency medium wave ultraviolet light, excimer laser, excimer light, etc., Chinese herbal medicine. And scattered type, generalized type and extremity type vitiligo can be treated with Chinese herbal medicine, immunomodulators (transfer factor, thymidine, etc.), system with glucocorticoids, phototherapy: narrow frequency medium wave ultraviolet, excimer laser, excimer light, etc., local topical medicine with the same limited type.
8, how to treat stable vitiligo?
The limited type or segmental type can be treated with topical psoralen drugs, glucocorticoids, nitrogen mustard, etc., autologous epidermal transplantation, local phototherapy or photochemotherapy: narrow-frequency medium-wave ultraviolet light, excimer laser, excimer light, etc., traditional Chinese medicine. Scattered type, pancytopenia and extremity type can be treated with TCM, phototherapy or photochemotherapy: narrow-frequency medium-wave UV, excimer laser, excimer light, PUVA, etc., autologous epidermal transplantation (exposed parts or parts requested by the patient), and its topical topical treatment is the same as that of limited type.
9.What are the precautions in vitiligo treatment?
(1) Long-term treatment and regular follow-up should be adhered to, generally the duration of a therapy is not less than 3 months.
(2) Should avoid trauma or exposure to the sun, especially in the progressive stage.
(3) Topical glucocorticosteroid treatment should be less than 10% of the body surface area of the white spots; patients with a white spot area greater than 90% of the body surface area and no efficacy, decolorization therapy can be recommended as appropriate.
(4) Supplementation with vitamin B, vitamin E, folic acid, zinc, etc. may be helpful.
10.What is the relationship between the efficacy of vitiligo and the time of onset?
Generally speaking, the shorter the onset time, the better the treatment effect, the longer the time, the more difficult the treatment. Therefore early diagnosis, early treatment is very important thing.
11, what is the relationship between the efficacy of vitiligo and the size of the white spot?
The effectiveness of the small area is high, the large area is poor, the cure time of the coin-sized white spot or palm-sized white spot is about 3 months to 15 months; the larger area, the circumference of the multi-patch distribution of the white spot generally need 2-4 years to cure.
12, what is the relationship between the efficacy of vitiligo and the location of the white spots?
The efficacy of vitiligo is in the order of face, head, neck, back, forehead, both iliac, waist, abdomen, hands and feet and mucous membrane parts. The face is easier to cure than other parts of the body. The cure rate of the white spots on the hands and feet and mucous membrane areas is lower.
13.What is the relationship between the efficacy of vitiligo and the type of rash?
The rate of healing of limited small area and ganglion type vitiligo can be as high as 95% or more, the area of large disease or sporadic lesions with large area or unstable disease healing time is longer or easy to repeat, while the rate of healing of generalized is less than 5%.
14.What is the relationship between the efficacy of vitiligo and the age of the patient?
The best efficacy of vitiligo for children with limited duration of disease.
15, what is the relationship between the efficacy of vitiligo and individual life?
16, need and vitiligo difference of common diseases
(1) white furfurace: that is commonly known as “worm spot”, “peach fungus”, manifested as facial round or oval superficial dry scaly hypopigmented spots, not as white as vitiligo color, the edge is also unclear. It is a good idea to have a look at the website. Most of them develop in the spring and autumn.
(2) Halo nevus also known as centrifugal acquired leukoplakia: now tend to be it may be a type of vitiligo, its occurrence is related to autoimmunity, mostly seen in young people, its skin lesions are characterized by single or multiple pigmented nevi surrounded by round or oval white spots in the shape of a halo, with clear edges.
(3) Age-related leukoplakia, also known as idiopathic pitting leukoplakia: mostly seen in middle-aged and elderly people over 50 years old, the trunk and limbs are the most common, and many scholars believe that this disease is one of the manifestations of skin degeneration in the elderly. The majority of the pitting white spots are round and oval, the diameter is generally not more than the diameter of the soybean cross-section, the maximum diameter does not exceed 1.0cm, the color is gradually changed from light white to porcelain white, the border is clear, does not expand or fuse, but the number of increasing trend with age.
(4) Mottled disease, also known as patterned leukoderma or restricted albinism, is an autosomal dominant genetic inheritance, and is born with white patches of varying size, irregular shape, and irregular distribution, but occurs more in the near-central part of the body, such as: chest, abdomen, limbs, etc. The normal skin color patches are interspersed in the white patches, or in the white patches or in the normal skin with deepened pigmentation. Hair on the affected area may turn white. Very few patients have only a small strand of white hair and no white spots of the skin.
17, how long does vitiligo treatment take?
The actual fact is that you can find a lot of people who have been in the business for a long time, so you must have the patience to stick to the treatment. Because many of the effects of treatment is often about 3 months to 6 months to clearly show. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things.
18, what is vitiligo phototherapy?
The main purpose of vitiligo phototherapy is ultraviolet light therapy, which includes PUVA therapy, NBUVB, 304nm high energy ultraviolet light, 308nm excimer laser, 308nm excimer light and so on.
19, what is vitiligo photochemotherapy (or PUVA therapy)?
The English abbreviation of photochemotherapy is called PUVA therapy, which refers to the treatment of vitiligo with long-wave ultraviolet radiation after topical or oral photosensitizer, which is more practical and effective for patients with limited or segmental type. The commonly used photosensitizer now is 8methoxypsoralen (8MOP). This therapy has a long course and generally requires 100 to 300 treatments to achieve the desired effect, but if there is still no significant pigmentation after 30 treatments, the therapy should be abandoned. Oral treatment is usually 8 MOP orally at 0.3-0.6 mg/kg 1 to 2 hours before irradiation, followed by long-wave UV irradiation 2 to 3 times a week. About 50% of patients respond well to this therapy, and the response to treatment is better for the face and trunk than for the extremities. Oral 8 MOP treatment should be treated with attention to its side effects and avoidance of light. Topical PUVA therapy can also be used for small areas of the rash.
20.What is NBUVB therapy?
NBUVB therapy is the abbreviation of narrow spectrum medium wave UVB therapy, narrow band UVB method does not need to be combined with oral 8MOP, its treatment wavelength is 311nm medium wave UVB, the treatment instruments used are full cabin type, half cabin type, folding type, half body, hand and foot special type, table lamp type, handheld type and other models suitable for different parts, due to its relatively low cost of treatment, in the domestic application of more Widely used. The treatment method is 2 to 3 times a week, the number of treatments dozen to hundreds of times ranging.
21.What is 308nm excimer laser light therapy?
The 308 nm excimer laser is a UV laser with a wavelength of 308 nm produced by xenon chloride as the laser excited gas. novak et al. found that the 308 nm excimer laser can promote the apoptosis of activated T cells in vitiligo lesions. The 308 nm excimer laser targeted treatment of vitiligo has the characteristics of high energy, high efficacy, convenience, safety and rapid onset of action, and the course of treatment is significantly shorter than NBUVB therapy, but because of its expensive instrument, the treatment cost is high, so only a few hospitals have carried out this therapy. In addition, there are 308nm excimer light treatment equipment, equipment costs and treatment costs are also lower than the former.
22.What is 304nm high-energy ultraviolet therapy?
304nm high-energy UVB is a special type of UVB, which emits a high-density UV beam through the equipment, with the help of liquid light guide fiber to make the effective light reach the lesion area, with high intensity, small spot area, can maximize the protection of normal skin, to achieve “target site treatment”. The actual treatment is a lot more precise and targeted than the traditional UVB treatment, so that the treatment period is significantly shortened, the number of treatments is significantly reduced, the efficacy is comparable to 308nm, the treatment cost is between 308nm excimer laser and NBUVB therapy, increasing the tolerance of patients.
23, what is the principle of phototherapy for vitiligo?
The mechanism of vitiligo treatment lies in its ability to directly promote the division and proliferation of melanin stem cells remaining in the affected area of skin lesions, accelerate pigmentation and achieve the purpose of melanin recovery in the affected area; induce T-cell apoptosis, reduce the production of autoantibodies and effectively inhibit the recurrence of vitiligo; in addition to the thermal effect on the affected area of the skin In addition, it has a thermal effect and biostimulation effect on the affected area of the skin, which effectively improves the local circulation and promotes its metabolism, which is conducive to the recovery of pigment and the fusion of melanin island with normal skin color as soon as possible.
24.What are the side effects of phototherapy?
PUVA requires oral photosensitizer, so it is necessary to avoid light after treatment. In addition to local reactions such as erythema and itching, there may be eye and gastrointestinal discomfort, etc. NBUVB, 308nm, 304nm phototherapy does not require oral photosensitizer, so there is no systemic discomfort, mainly local erythema, blistering, slight pain and other tolerable discomfort, which can be effectively controlled by dose adjustment. The treatment of vitiligo can be effectively controlled by adjusting the dose.
25, what are the advantages of Chinese medicine in treating vitiligo?
26, vitiligo patients need to avoid eating vitamin C food?
The actual fact is that you will not need to. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The epiphysis is prone to dislocation or separation, while bone resorption continues, resulting in generalized osteoporosis and atrophy. In addition, the formation of dental bone matrix is impaired, and the teeth are dysplastic and prone to loosen and fall out. The patient does not have to talk about C.