The main component of gas is carbon monoxide, which can combine with the body’s hemoglobin after entering the body, affecting the transport of oxygen in the blood and causing hypoxia in the organism. Most patients with mild or moderate gas poisoning do not have sequelae, but for patients with severe gas poisoning, some patients will have sequelae, mainly including mental abnormalities, cerebral edema, delayed encephalopathy, dementia, etc. 1. mental abnormalities: early patients can show memory loss, slow reaction, reduced speech, indifference, and then gradually appear crying and laughing, irritability, depression and other mental symptoms; 2. cerebral edema The brain is most sensitive to hypoxia, which can lead to capillary degeneration and increased permeability in the brain, causing cerebral edema; 3, late-onset encephalopathy: in severe cases, the brain and spinal cord will have varying degrees of congestion, hemorrhage, and the formation of thrombus, causing local softening or necrosis, and extensive demyelination of the white matter of the brain can cause late-onset encephalopathy; 4, dementia: manifested as dull expression, panic gait, urinary and fecal Other: some patients will have partial limb movement disorder, sensory disorder and visual disorder, muscle tonic spasm, frequent convulsive seizures, etc. The influencing factors that are likely to produce sequelae after coal gas poisoning mainly include: 1. Patients who are over 40 years old, especially the elderly, who are in poor vascular status themselves and are prone to combined cerebral arteriosclerosis and stenotic lesions; 2. Patients with previous underlying diseases such as hypertension, diabetes, hyperlipidemia, etc.; 4. Patients who have received significant mental stimulation after coal smoke poisoning; 5. Complications such as infection and cerebral infarction appeared; 6. Patients with moderate or severe poisoning were improperly treated in the acute stage or prematurely stopped treatment.