Recent studies have found that alcohol consumption is an important risk factor for atrial fibrillation (AF). Alcohol consumption can lead to atrial anatomical and electrical remodeling, which affects the autonomic nerves and other risk factors for AF, leading to the development of AF. In addition, alcohol consumption also affects the prognosis of AF treatment, thus increasing the risk of adverse events in AF. I. Definition of Holiday Heart Syndrome Increased alcohol consumption can trigger a heart rhythm disorder, known as atrial fibrillation. It occurs independently of a previous history of atrial fibrillation and can occur when excessive alcohol is consumed. This disease is named “holiday heart syndrome”. Second, the relationship between alcohol consumption and AF Researchers [2] found that at least among elderly people aged 55 years or older at high risk of cardiovascular disease or diabetes, either moderate or high alcohol consumption was significantly associated with an increased risk of subsequent new-onset atrial fibrillation, and among moderate drinkers, the risk of atrial fibrillation among heavy drinkers was roughly similar to that of those who had a heavy drinking habit. samokhvalov et al. The study by samokhvalov et al. found a critical value of alcohol associated with an increased risk of atrial fibrillation, again revealing a dose-dependent curve of alcohol and atrial fibrillation. Alcohol consumption increases the risk of respiratory sleep apnea syndrome and atrial fibrillation About one-half of patients with atrial fibrillation may have obstructive sleep apnea syndrome. Men who drank more than the standard amount of alcoholic beverages per day had a 25% increased risk of obstructive sleep apnea syndrome, which may be associated with a temporary reduction in oropharyngeal muscle tone that inhibits arousal mechanisms and leads to segmented sleep. Fourth, the mechanism by which alcohol consumption increases atrial fibrillation The stability of atrial myoelectric activity depends on the balance of vagal and sympathetic activity. Excessive enhancement of either activity can lead to arrhythmias. The rapid increase of alcohol concentration in the blood caused the sensitivity of the atrial muscle to the autonomic nervous system to change in different states of the body, and accelerated the imbalance of the autonomic nerve, which increased the vagal tone, increased the sensitivity of the atrial muscle to acetylcholine, shortened the atrial muscle’s expiration period, thus accelerating the formation of multiple folding loops in the atria, and led to functional paroxysmal atrial fibrillation. In 122 patients who underwent pulmonary vein electrical isolation, the arrhythmia-free survival rate was found to be 81% at 1 year, and the rate was 69% for light to moderate drinkers (1-4 standard drinks/week for men; 1-7 standard drinks/week for women), but only 35% for heavy drinkers.