Urticaria is a common clinical skin disease, which is a limited edematous reaction due to dilation and increased permeability of small blood vessels in the skin and mucous membranes, usually subsiding within 2-24 hours, but easily recurring. Urticaria, once acquired, does not become a permanent disease. Urticaria can be clinically divided into acute urticaria and chronic urticaria. Acute urticaria can usually be cured after active treatment, and recurrent urticaria for more than 6 weeks is called chronic urticaria, while chronic urticaria may occur repeatedly after treatment. In the case of acute urticaria, active treatment should be taken to control the condition. At this time, anti-itch medications such as calomel lotion can be used to relieve discomfort, H1 receptor antagonists can be used for treatment, along with vitamin C and calcium to reduce the permeability of blood vessels, and then combined with antihistamines to relieve the symptoms of urticaria. Antispasmodic drugs, such as atropine, can be used if symptoms of abdominal pain are present. Generally, most patients can be cured with aggressive treatment. If chronic urticaria develops, treatment can be switched to two antihistamines or combined with some immunosuppressive drugs, such as cyclosporine, as well as biological agents, such as omalizumab, which can usually control the disease. In daily life, patients with urticaria should actively search for allergens, and at the same time avoid eating foods that may trigger the disease, commonly soy products, seafood, nuts and so on. Usually pay attention to indoor ventilation, ensure indoor cleanliness, and ensure regular rest and rest to reduce the recurrence of hives.