For patients with high hypotension, the following drugs can be applied as the first choice: 1, the first can be applied ACEI class of drugs, this drug is also known as angiotensin converting enzyme inhibitors, representative drugs are captopril, benazepril, perindopril, fosinopril, etc.. Not only can have a strong role in reducing low pressure, but also has a protective effect on the heart and kidneys, can reverse ventricular remodeling to reduce proteinuria; 2, angiotensin II receptor antagonist near, also known as ARB class of drugs, the representative drugs are Crosartan, Valsartan, Irbesartan, Temisartan and so on. This kind of drugs can reduce low pressure, but also for increasing insulin sensitivity has a certain effect; 3, calcium channel antagonists, this kind of drugs can be applied, for example, nifedipine, amlodipine benzoate.