Benign clavicle tumor has no obvious symptoms in early stage, and malignant one has pain, local swelling, pathological fracture and other manifestations in early stage. 1. Benign clavicle tumor usually has no obvious symptoms in early stage, after which local swelling may appear, hard lumps may be touched, and even activity limitation and bone destruction may occur. 2. Malignant clavicle tumor is less primary, and is mostly transferred from other parts. Clinical symptoms include local severe pain, local swelling and hard lump, pathological fracture, etc. It is also accompanied by malignant tumor’s malignant manifestations such as lethargy and fatigue. The treatment of benign clavicle tumor is mostly after obvious symptoms appear, and surgery can be considered after checking in hospital to exclude malignant possibility. Malignant clavicle tumors should be diagnosed by combining the history of malignant tumors in other parts of the body and typical clinical manifestations, and opioid analgesics should be chosen for pain treatment along with the treatment of the primary tumor.