There is no so-called “the best treatment for chronic urticaria”, the doctor needs to take individualized treatment plan according to the patient’s personal situation, the degree of illness and the cause of the disease, including general treatment, drug treatment or other treatment. 1. General treatment: some of the causes of chronic urticaria are not clear, but a small number of chronic urticaria can be clear cause, this situation should first remove the cause, away from the triggering factors, to keep the skin clean and dry; in addition, patients need to keep in a relaxed mood, do not be emotionally stressed or anxious. 2. Drug therapy: chronic urticaria medication is individual differences, oral diclofenac tadalafil, ebastine and other antihistamines to relieve the symptoms; symptoms are serious, can follow the doctor’s instructions for the joint application of immunosuppressants, such as cyclosporine, tacrolimus, etc.; patients with persistent symptoms can be under the guidance of the doctor applying biologics treatment. 3. Other treatments: For patients with long-term recurrent attacks, long-wave ultraviolet irradiation, medium-wave ultraviolet irradiation can be used at the same time to alleviate the symptoms. If diagnosed with chronic urticaria, it is recommended that patients follow the doctor’s instructions according to the individual situation, choose the appropriate program for treatment, so as to achieve a better therapeutic effect, do not use drugs privately, so as not to cause serious adverse reactions.