(1) Ask the patient about the occurrence of control after taking the medication, whether there is headache, dizziness, drowsiness, weakness, nausea, vomiting, abdominal pain, diarrhea, hair loss, skin itching, rash, etc. (2) Check the general condition of the patient, including mental status, intellectual condition, whether the skin has redness, swelling, papules, hair growth or loss, gum growth, liver pressure pain and enlargement, etc. (3) For some patients whose etiology is not clear yet, general neurological examination, such as pathological reflexes, should also be performed frequently during treatment in order to find further clues of brain lesions. If necessary, EEG, lumbar puncture for cerebrospinal fluid, cerebral angiography, CT, magnetic resonance imaging, cervical Doppler, cervical spine X-rays and related laboratory tests, such as cysticercosis complement test, can also be reviewed. The etiology of the disease will be further clarified through these examinations. (4) In the beginning and middle of treatment and during the beginning and reduction of medication, EEG should be frequently rechecked to observe the control of epileptic discharges in the brain in order to guide the adjustment of medication dose and reduction rate. (5) Frequent review of blood picture, including white blood cell count, classification, platelet count and bleeding and clotting time. This test should be repeated once every 3-5 days at the beginning of treatment (within 2-3 weeks) to detect abnormal changes in time, and once every 1-3 months thereafter. (6) Regularly review liver function, including transaminases, jaundice index and blood ammonia, etc. (7) Regularly check blood calcium and, if available, folic acid, T3 (triiodothyronine), T4 (thyroxine) and other endocrine hormones to detect drug-induced endocrine and metabolic abnormalities. (8) Immunological examination, including immunoglobulin A, M, G and other indices, in order to detect immune dysfunction. (9) Periodically check blood and drug concentrations to guide medication use.