The main treatment for urticaria is medication. Antihistamines such as fexofenadine, loratadine, desloratadine, and ebastine can be taken orally for treatment. If you need to use drugs, you need to use under the guidance of a doctor. Urticaria can be treated with second-generation non-sedating or low-sedating antihistamines for anti-allergic treatment. Commonly used drugs include: fexofenadine, loratadine, desloratadine, ebastine, and epinastine. When one drug is not effective, two antihistamines can be used simultaneously to control symptoms. If necessary, it can be combined with immunosuppressants such as cyclosporine, or biological agents such as omalizumab for treatment For patients with severe itching caused by hives, medications such as benadryl cream and glycerite lotion can be used to apply to the affected area to relieve symptoms. If you need to use drugs, you need to use them under the guidance of your doctor.