In general, the amniotic fluid flows out and the amniotic cavity is connected to the outside world. Bacteria can cause retrograde infection to the fetus, and if the amniotic fluid ruptures for a longer period of time, the greater the risk of infection. Amniotic fluid contains fetal fat, meconium and other substances, which is a better culture medium for bacteria. If the amniotic fluid ruptures for more than 12 hours, it will easily cause bacterial upstream infection and lead to serious consequences. In addition, amniotic fluid has a buffering effect on extrusion, thus protecting the fetus and umbilical cord from pressure. After the water breaks, the amniotic fluid gradually decreases, and the protective effect on the fetus gradually decreases, so when the amniotic fluid decreases to a certain level, it can cause fetal hypoxia and asphyxia. Therefore, 12 hours after the rupture of amniotic fluid without delivery, antibiotics are needed to prevent intrauterine infection. In addition, when the amniotic fluid has not ruptured for more than 24 hours, it is necessary to use oxytocin to facilitate delivery to avoid fetal distress.