Vulvar leukoplakia and vaginitis are not directly correlated, so the order of treatment is not prioritized, and if both vulvar leukoplakia and vaginitis are present, they should be treated at the same time. Vulvar leukoplakia and vaginitis are two different diseases, but both can be manifested as vulvar itching, so they are not prioritized in the order of treatment, and treatment should be started at the same time if they exist at the same time. The common symptoms of vulvar leukoplakia include vulvar itching and burning sensation, often accompanied by hypopigmentation, which may be due to vulvar squamous epithelial cell hyperplasia or vulvar sclerosing tesserae, which can be treated with hormone topical application, laser and freezing. The common symptoms of vaginitis include increased vaginal discharge, itching, odor and other symptoms, which can be treated with vaginal plugs such as metronidazole suppositories and diazotide suppositories. Vulvar leukoplakia and vaginitis have some similar symptoms, and if they develop at the same time, they should be treated together, in no particular order.