Parkinson’s disease is a chronic neurodegenerative disease, and treatment should not only focus on the immediate future, but also requires long-term management, taking into account the long-term effects of treatment. With large doses of levodopa, involuntary choreiform movements and other difficult-to-regulate dyskinesias can occur in the short term, whereas with small doses, the incidence of dyskinesias is not high even with long-term administration. In principle, the minimum dose should be considered to maintain a relatively satisfactory therapeutic effect, following the principle of “long flow of water, not full effect”. Patients with Parkinson’s disease should start with small doses and gradually increase the dose to reduce the occurrence of nausea, vomiting and other gastrointestinal reactions and increase the patient’s tolerance of the drug on the one hand; on the other hand, to avoid the emergence of xerostomia soon. The general honeymoon period of drug treatment is 3-5 years. If the disease duration is too long and the effect of high-dose drug control has been minimal, the patient can be treated by deep brain electrical stimulation surgery, after which the patient can resume normal life, but a detailed preoperative evaluation is needed to determine whether the patient has the opportunity for surgical treatment. Patients with Parkinson’s disease suitable for DBS treatment should meet the following conditions 1. primary Parkinson’s disease 2. taking levodopa used to have good efficacy, acute methyldopa shock test is greater than 30 points 3. drug efficacy has gradually decreased or side effects have appeared 4. age is not more than 80 years old 5. the disease has begun to affect normal work and life 6. the patient and his family understand the expectations of surgery; not suitable for DBS treatment Who are the patients with Parkinson’s disease? 1.Patients with advanced Parkinson’s disease with severe disease 2.Patients with Parkinson’s disease with severe dementia and psychiatric symptoms 3.Patients with severe cardiopulmonary disease and severe hypertension 4.Patients with severe bleeding tendency 5.Patients who cannot cooperate with postoperative program control and those who cannot accept implants 6.Patients who are over 80 years old and have poor general status and cannot tolerate surgery After deep brain electrical stimulation surgery, with the gradual recovery of motor function, patients To actively carry out rehabilitation training. As the disease progresses, advanced symptoms such as low voice, unclear pronunciation, difficulty in striding and poor walking balance are problems that patients with Parkinson’s disease must face. To address these symptoms, it is necessary for patients to actively engage in rehabilitation training to slow down the decline in limb motor function.