Can allergic purpura nephritis be completely cured?

The prognosis of allergic purpura nephritis varies widely, and pediatric patients may recover spontaneously with complications such as hypertension, massive proteinuria, and early renal impairment, which have a poor prognosis and cannot be cured. The main factors affecting its prognosis include: age of onset, children have a better prognosis than adults, clinical manifestations of minor microscopic hematuria and proteinuria (urinary protein <0.5g/d) in patients with purpura nephritis, the disease may be spontaneously cured. Those who present with hypertension and large amounts of proteinuria have a poor prognosis. Those who develop early renal impairment have a poor prognosis. Usually the pathologic damage in this disease, as in IgA, is damage to the cells of the tethered zone of the kidney. Pathologic changes, hyperplasia and insertion of damaged cells of the tunica albuginea lead to damage to the endothelial cells of the glomerulus. This leads to the appearance of urinary protein and urinary occult blood, which may lead to the deterioration of renal function, chronic renal insufficiency, or even uremia. Clinical treatments usually include anti-inflammatory treatment with prednisone acetate and anti-immunity treatment with cyclophosphamide. It is recommended that allergic purpura nephritis timely to the hospital, under the guidance of the doctor symptomatic treatment.