The patient, Qie XX, male, 67 years old, from Wangdu County, Hebei Province, was suffering from cerebral thrombosis after the application of various drugs (mannitol, pulsatilla, salvia, etc.) caused allergic purpura, purpura nephritis, mainly manifested as a rash on both thighs, hematuria ++, proteinuria ++, in the county hospital had applied cyclophosphamide and other treatment did not improve, referred to my out of hospital treatment. The main treatment: continue to use cyclophosphamide, from 0.2 every other day to 1 gram impact, once a month, at the same time add homemade special Chinese medicine kidney fukang capsule and nephritis capsule treatment, 3 months later hematuria, proteinuria gradually reduced, half a year later hematuria disappeared, protein close to normal, 2 years later urine test completely turned negative, follow-up 5 years without recurrence. Tip: In addition to children, allergic purpura is also easy to occur in the elderly, especially when applying a variety of drugs is easy to induce, many doctors think it is difficult to cure, the prognosis is poor. We insist on the combination of Chinese and Western medicine in treatment, cyclophosphamide shock should be insisted on with a full course of treatment, Chinese medicine plays an auxiliary role, which can reduce the side effects of cytotoxic drugs, but also can unblock blood channels, dispel dampness and clear heat. In addition, it is necessary to figure out the allergen as much as possible to prevent recurrence.