Pinworm disease is a common parasitic disease caused by pinworms parasitizing the end of the human small intestine, cecum and ileum, and is most common in early childhood, with the main clinical manifestations being nighttime itching of the perineal area and perineum, and also the following manifestations: 1. local symptoms: mainly intense itching of the perineal and perineal areas, which can cause lesions and secondary inflammation or infection as the child scratches the itchy area; 2. systemic symptoms: manifested as Nausea, vomiting, abdominal pain, lack of appetite and other gastrointestinal irritation symptoms, as well as anxiety, insomnia, night terrors, inattention and other mental symptoms; 3, other symptoms: in a few cases, pinworms can ectopically parasitize or invade other organs, causing diseases such as appendicitis, vaginitis, pelvic inflammatory disease and peritonitis. Eosinophilia is seen in the peripheral blood. Since pinworms do not lay eggs in the intestine, eggs are not easily detected by stool examination. Generally, at night, after the child is asleep, the clinic observes whether small white nematodes appear in the perianal skin folds, or uses tape to remove eggs from the folds for microscopic examination. After the diagnosis is confirmed, deworming treatment is required, and drugs such as mebendazole, albendazole or thiamphenicol can be used under the guidance of a doctor, or local anti-itch ointment can be applied. In addition, parents should urge their children to develop good hygiene habits and wash their hands carefully before and after meals. Cut nails regularly, disinfect toys, utensils and bedding, correct the habit of sucking fingers or toys, and wear full-crotch pants as early as possible.