Visceral disease is divided into myofascial-derived visceral disease and true visceral disease. Myofascial-origin visceral disease is defined as a visceral lesion in which the presence of MTrPs occurs in connection with the myofascial-visceral junction and there are no concomitant medical-pathologic (unsupported by imaging or laboratory data) changes. The hallmark diagnostic indicator of visceral disease of myofascial origin is the presence of myofascial trigger points (MTrPs) thoracolumbosacral gluteo-abdominal muscles and remote muscles. Diagnostic identification of visceral per se lesions or lesions of myofascial origin; can be made by performing a rapid test of appropriate muscle movement to determine if there is myofascial damage; palpation of muscles to determine if trigger points are present; true visceral pain, which will be accompanied by changes in medical pathology (imaging and laboratory support) The development and prolonged persistence of visceral disease and MTrPs can be explained by a variety of mechanical, nutritional, metabolic, and affective muscle strains, circulatory, and pain psychologic factors. Explanation. Mechanical factors such as direct trauma, chronic poor posture or body mechanics, ergonomic stress, joint hypermobility, lower extremity isometrics, scoliosis, and pelvic torsion can increase muscle strain. These mechanical factors can occur from previous surgeries, birth trauma, childhood falls, injuries, accidents, illnesses, physical or sexual abuse, and repetitive patterns of movement. Such events can be pre-existing injuries that lead to future myofascial dysfunction, and different myofascial injuries can cause corresponding visceral disease. Trigger points in the thoracolumbar, sacral, and gluteal abdominal muscles can be triggered by the fact that pain in the abdominal wall tends to reflect back to the abdominal wall, prompting tense contractures of the abdominal muscles, which ultimately generates trigger points in the myofascia causing the muscular movement of the endplates, which in turn act on the corresponding visceral organs to cause persistent or even worsening pain in the abdominal area. When clinicians do not realize the role or weight of trigger points in abdominal pain, they make a plan that only targets the corresponding organ and when implemented, it does not relieve or cure the pain, and sometimes only partially relieves the pain. And for an understanding of the trigger point in the visceral pain in the degree of participation, but often easy to solve the visceral pain, such as the author in the clinic on some of the use of instruments or laboratory tests combined with the clinical symptoms diagnosed true abdominal visceral lesions caused by pain, including acute appendicitis, acute and chronic pelvic inflammatory disease, gastroduodenal and so on have achieved very good results. Although this type of pain is true visceral pain (can be diagnosed by relative signs and instruments or laboratory tests), but does not seem to be completely cut off from the abdominal muscle trigger point but with the trigger point inextricably linked to the inextricable links to inactivate the trigger point in the clinical experience is very clear proof of the ability to cure or alleviate this type of true visceral pain. There is also a category of visceral pain that is directly induced by trigger points in the abdominal muscles. Trigger points in the abdominal muscles not only cause pain in the abdomen, flanks, and back, but they are also associated with pain in the abdominal viscera and the male and female genital organs. These diverse and often secondary abdominal trigger points are “very misleading in terms of diagnosis,” and the manifestations triggered by the trigger points may be similar to those of other abdominal disorders. It is important to note that identifying the presence of trigger points in the abdominal muscles does not mean that pain due to true visceral disease has to be ruled out, and that abdominal trigger point symptoms may still be an important factor even after visceral disease has been demonstrated to be present, as visceral disease can indeed contribute to the development of trigger points due to tension and contracture of the abdominal, lumbar, and sacral muscles. Trigger point therapy may be a good option when it is not clear whether the pain is caused by a true visceral lesion.