The phenomenon of coughing when lying down occurs, it is necessary to do electrocardiogram and cardiac ultrasound examination to exclude the cough caused by cardiogenic asthma, especially left heart failure, the amount of returning blood increases when lying down, inducing pulmonary stasis, when lying down the coughing symptoms will appear, it is necessary to carry out targeted treatment for the primary heart disease. If there is no obvious abnormality in the heart, it means that there may be infection in the respiratory system. Chest X-ray and lung CT examination can be improved to clarify the presence of infection when there is a large amount of secretions in the respiratory tract, which will stimulate the respiratory tract and cause coughing, and at the same time, the bronchial tree will be compressed by the surrounding lung tissues when lying down, producing relative narrowing, which will also easily induce coughing symptoms. It is necessary to choose appropriate antibiotics or antiviral drugs for anti-inflammatory treatment in response to the infection.