Pituitary adenomas are benign tumors that occur in the adenohypophysis and are among the most common intracranial tumors. According to the secretory function of tumor cells, pituitary adenomas can be divided into two categories: secretory (functional) adenomas and nonsecretory (nonfunctional) adenomas. In the last half century, especially in the last two decades, with the clinical application of pituitary hormone radioimmunoassay, CT and MRI, especially the in-depth understanding of pituitary microadenoma, the incidence of pituitary adenoma, especially prolactin adenoma, has been increasing year by year. An epidemiological survey has shown that the incidence of prolactin adenoma is as high as 1:1050 in women and 1:2800 in men, while autopsy studies have found that the detection rate of prolactin adenoma is 7-21%. These figures may seem alarming, but they do reflect the high incidence of pituitary adenomas in one way or another. Pituitary adenomas can be divided into the following categories: 1) growth hormone cell and lactin cell adenomas; 2) adrenocorticotropic hormone cell adenomas; 3) gonadotropin cell adenomas; 4) thyrotropin cell adenomas; 5) others: including anaplastic cell adenomas, eosinophilic granulomas, and undifferentiated adenomas. Clinical manifestations: pituitary adenomas present with two main groups of symptoms: secretory dysfunction and local compression We are now going to talk about prolactin adenomas. In women it is mostly seen in the age of 20-30 years. The typical clinical manifestations are amenorrhea, lactation and infertility, which are often seen in gynecology departments as gynecological diseases, and only when doctors suspect whether it is a pituitary tumor is a CT or MRI examination of the head prescribed. For example, some male patients have early hypogonadism, lack of libido, impotence, and sperm reduction, and most of them go to the male department, but the treatment is not effective for a long time. Many of them are male patients around 40-50 years old with obvious breast enlargement. Some of them go to general surgery to be admitted with male breast enlargement, which is surgically removed to prevent cancer, and after removal, the residual glands continue to grow or have a serious decrease in sexual function, some of them have headache and obvious loss of vision, and some of them even go to many departments such as male medicine, general surgery and ophthalmology, and spend a lot of medical expenses, and finally go to neurology for Some patients even go to many departments such as male, general and ophthalmology, and spend a lot of money on medical treatment. There are also some patients who have inadvertently suffered head trauma during the treatment period and went to the neurosurgery department of the hospital, where a pituitary adenoma was unintentionally discovered by a head CT. For pituitary adenomas, especially small prolactin adenomas, they can be cured by oral medication without surgery, while those with obvious occupancy and those who are not obvious with medication will be considered for surgery, which in most cases does not require craniotomy and can be solved by a nasal approach. This also solves the patient’s fear, which is a widely performed and proven surgical procedure.