Older women who like to eat a lot of starch and sugar may have a higher risk of developing a less common but more deadly form of breast cancer, a European study has found. After studying nearly 335,000 European women, researchers were not able to prove that sweets, French fries and white bread cause breast cancer, but found that they may be a potential risk factor for a rare type of breast cancer. The study found an association between high “glycemic load” and “ER-negative (lacking estrogen receptors)” breast cancer. High glycemic load refers to foods that can cause a rapid rise in blood sugar, such as foods made from flour, potatoes and sweets. In the 12-year study, 11,576 of these people developed breast cancer. Based on the dietary questionnaire the women filled out at the beginning of the study, no association was found between glycemic load and breast cancer. ER-negative breast cancer accounts for a quarter of all breast cancers, and this type has a worse prognosis than ER-positive because it grows rapidly and is not sensitive to hormone-based treatments. The study was conducted by the Stanford Cancer Prevention Institute. Associate Professor Christina Clarke from the Stanford Cancer Prevention Institute believes that the results of this study are an important guide to future research, as little is known about the etiology of ER-negative breast cancer. Diets with high glycemic load are associated with high insulin secretion, which not only lowers glucose but also makes it relevant to certain cancers because of its potential to promote tumor growth. Although no specific breast cancer prevalence factors have been clearly identified, the findings may serve as a warning to reduce the intake of refined carbohydrates and promote a healthier, balanced diet of lean meats, vegetables, “good” fats and high-fiber grains.