The principles of myasthenia gravis management are basically the same, and the specific treatment methods are as follows: 1) firstly, keep the airway open, such as mechanical ventilation to maintain and improve the respiratory function; 2) actively control the infection, and choose effective antibiotics to control the infection; 3) maintain the water and electrolyte balance; 4) apply glucocorticoids for shock therapy; 5) remove the antibodies in the blood through plasma exchange; 6) inject human immunoglobulin for shock therapy to regulate the immune function. Finally, the nature of myasthenia gravis needs to be determined before further treatment: patients with myasthenia gravis need to apply anticholinesterase inhibitors, such as intramuscular neostigmine, while for cholinergic crisis, cholinesterase inhibiting drugs need to be stopped and atropine can be applied for treatment. Myasthenia gravis is very critical and once it develops, patients should go to the hospital for resuscitation treatment in time. Myasthenia gravis crisis is the most critical state for patients with myasthenia gravis, which refers to the state of severe respiratory insufficiency caused by the aggravation of the patient’s own condition or repeated infections or improper treatment, etc. According to the different causes of myasthenia gravis, it can be divided into the following three crises: 1. myasthenia gravis: refers to the insufficient dosage of neostigmine, often caused by infection, trauma, drug reduction; 2. cholinergic crisis: refers to the excessive dosage of neostigmine, in addition to the symptoms of myasthenia gravis, patients often have symptoms caused by excessive accumulation of acetylcholine, such as nausea, vomiting, abdominal pain, diarrhea, excessive sweating, excessive airway secretions, muscle tremors, etc.; 3. Antalgic crisis: often difficult to identify clinically.