The main clinical manifestations of brachial plexus neuropathy include muscle weakness and atrophy of the shoulder girdle, upper extremity and thoracic back muscles, and numbness, pain and hyperalgesia in the sensory areas of the skin corresponding to the affected brachial plexus nerve branches. How to diagnose muscle weakness and muscle atrophy of the shoulder girdle, upper extremity and thoracic back muscles? 1, brachial plexus neuropathy in the case of non-same plane cutting injury, any 2 or more brachial plexus nerve branches involved at the same time should be considered to have the possibility of brachial plexus neuropathy. Domestic Gu Yudong emphasized the importance of the involvement of the 5 major nerves of the upper extremity for the diagnosis of brachial plexus neuropathy and suggested that the presence of brachial plexus nerve injury should be considered in one of the following cases: ① joint injury of any 2 nerves in the axillary nerve, musculocutaneous nerve, median nerve, ulnar nerve and radial nerve. (ii) Combined shoulder or elbow dysfunction of any of the median, ulnar, and radial nerves. (3) Combination of any of the median nerve, ulnar nerve and radial nerve with medial forearm cutaneous nerve injury. 2.Intercostal neuralgia is not difficult to diagnose based on its pain distribution area and characteristics. The diagnosis of damage to lumbosacral nerve roots, plexus and nerve trunks mainly depends on clinical manifestations, and it is sometimes difficult to differentiate them because they are in a continuous relationship with each other in space, such as damage to the lower sacral plexus, sciatic nerve and common peroneal nerve can cause the same motor dysfunction. Neurophysiological examination may be helpful in localizing the diagnosis. CT and MRI of the lumbosacral spine and pelvis may provide a basis for finding the cause. 4.Sciatica is not difficult to diagnose according to the distribution of pain, radiation path and pressure site, the trigger of pain increase and decrease, Lasegue’s sign, weakened ankle reflex, decreased sensation in the lower leg and lateral dorsal foot. The symptoms and signs of lumbar disc herniation may occur suddenly or insidiously, or after trauma. Lumbar spine X-ray or MRI, pelvic and rectal examinations can help to exclude lesions such as tumors.