Pituitary adenoma is the 3rd most common tumor in the nervous system. It is deeply located and surrounded by important structures such as the bilateral internal carotid arteries, the actinic nerve, the talonavicular nerve, the adductor nerve, the optic nerve and the pituitary stalk. Therefore, the principle of treatment for pituitary tumors is comprehensive, which means that a combination of different treatments is needed to control tumor growth. These treatments include surgery, radiation therapy and medication. Some pituitary tumors are soft or have not yet invaded important structures, so there is a chance of complete surgical removal of the tumor. Even for some pituitary tumors that invade the cavernous sinus, with the development of endoscopic surgery, special surgical techniques can be used to improve the resection rate of the tumor. In softer pituitary tumors, it is easier to remove the main body of the tumor, and the peripheral tumors tend to remain. For tumors with a harder texture, the suprasellar portion is easy to be left behind. For tumors that invade the cavernous sinus, total resection of the tumor in the cavernous sinus is often not possible. According to the specific conditions of different patients, we use different techniques such as diving endoscopic technique, extracapsular separation, combined with intraoperative ultrasound, navigation and the use of special instruments to remove the residual tumor in the periphery and improve the surgical cure rate.