Thyroid nodule grade 2 that is TIRADS category 2 nodules, there are diffuse lesions may be nodular goiter, thyroiditis and other diseases, the treatment of different diseases is different. 1. Nodular goiter: nodular goiter, also known as adenomatous goiter, refers to multiple nodules formed by endemic goiter and sporadic goiter. Nodular goiter generally does not require treatment. TIRADS category 2 is a benign nodule that can be followed up regularly; if the swelling is too large and leads to symptoms of compression or cosmetic problems, it can be treated with surgery. 2. Thyroiditis: Thyroid nodule combined with thyroiditis can be manifested as diffuse lesions, for example, subacute thyroiditis, can be treated with glucocorticosteroids such as prednisone; Hashimoto’s thyroiditis, hypothyroidism can be treated with levothyroxine sodium, and surgery can be considered for those who have symptoms of compression and those who are suspected to have malignant lesions. It is recommended that patients with diffuse lesions in grade 2 thyroid nodules should consult a doctor in time and take targeted treatment after a clear diagnosis.