Itching on the inner side of the labia majora can be caused by a variety of factors, and is clinically common in gynecological diseases caused by unclean vulva or bacterial infection, as well as inflammatory manifestations caused by systemic diseases such as diabetes and anemia. In addition, local itching symptoms can also occur when the vulva is stimulated by undesirable factors, and the differential diagnosis should be made after perfect examination: 1. Gynecological diseases: common diseases are trichomonas vaginitis and fungal vaginitis, and abnormal inflammatory secretions can appear in the vulva under the influence of pathogens, and the symptoms of vulvar itching can occur by stimulating the labial area. Some patients develop fungal infections of the vulva, leading to vulvar lichen planus, which can also cause itching symptoms. Patients need to improve the examination of vaginal and cervical secretions to clarify the specific type of infection, which can be treated with anti-itch lotion, clotrimazole suppositories or metronidazole suppositories administered intravaginally. In addition, the sexually transmitted disease condyloma acuminata, in addition to vulvar itching symptoms, can be accompanied by superfluous organisms as well as pain, foreign body sensation, etc., need to be clearly diagnosed through HPV examination and pathological examination, feasible laser treatment, trauma application interferon coating, to avoid infection; 2, systemic diseases: mainly seen in patients with diabetes, poor blood sugar control, vulvar mucosa can be impregnated and irritated resulting in itching. In addition, severe anemia and intrahepatic cholestasis can affect the skin and mucous membrane, and some patients may have itching symptoms, which should be actively treated for the primary disease; 3. Adverse vulvar stimulation: if the underwear worn is not breathable or made of chemical fiber, it may induce itching of the labia majora. If you are in menstruation, menstrual blood will also stimulate the vulvar skin and mucous membrane, and the use of sanitary napkins with inappropriate materials or untimely replacement will cause itching on the inner side of the labia majora. You should pay attention to menstrual hygiene, wear loose cotton underwear and change sanitary napkins in time.