Mastocytosis is a benign disease, not cancer. It is caused by an increase in the level of estrogen in the body, which leads to hyperplasia of the terminal ducts and follicles of the glands in the breast tissue and the surrounding fibrous tissue, with lymphocytic infiltration. Mastocytosis is divided into three types: 1. Breast pain disorder: also known as breast tissue hyperplasia, characterized by periodic pain in the breast, mostly seen in women aged 20-40 years, pain related to the menstrual cycle, premenstrual symptoms are obvious, after the relief. The correct examination method breast can not feel the lump, most of the performance of local tissue thickening of the diffuse distribution of the granular area, so also known as swollen granular breast. Breast pain is mostly self-limiting and can be relieved after marriage and pregnancy, and no cancer will occur. 2, breast adenopathy: Most often seen in young and middle-aged women, often a limited lump with pain in one breast, or bilateral onset, the pain is related to the menstrual cycle. Most of them occur in the upper part of the breast, and the lump is small, about 1-3 cm in diameter. The masses are small, about 1-3 cm in diameter. They are not hard and are not well defined by the surrounding tissue. The early stage of mammary gland adenopathy is lobular hyperplasia, which is not cancerous in this fashion, but there is a 1% cancer rate in the middle and late stages of mammary gland adenopathy. 3, cystic hyperplasia of the breast: common in middle-aged women, manifested as breast lumps, but a single larger lump, spherical, smooth surface, cystic or solid feeling. It can also present as multiple cystic nodules in the breast. About one-third of patients may have pain and tenderness in the early stages, but it is not significant, and sometimes there is nipple discharge. About 3=8% of cystic hyperplasia of the breast can become cancerous, so we should be especially vigilant and follow up regularly.