In some patients with moderate to severe endometriosis, after surgery, in order to prevent recurrence of endometriosis or further shrinkage of the residual lesions, the doctor may recommend that the patient continue treatment with medication for a period of time. Patients should choose the most suitable medication according to their condition, financial condition, whether they want to get pregnant or not, and the doctor’s advice. 1. Mafron: continuous or cyclic dosing for 3-6 cycles. (1) Cyclic dosing regimen: take one tablet orally every night from the 5th day of menstruation for 21 days, and start a new cycle of treatment from the 5th day of menstruation in the next cycle after discontinuing the drug. If your menstrual period does not come one week after stopping the drug, come to the hospital for examination. (2) Continuous dosing regimen: Take one tablet orally every night from the 5th day of the menstrual cycle for 6 months. Continuous dosing usually does not result in menstrual flow. Caution: If there is a little vaginal bleeding during the medication period, continue to take the medication. If the bleeding is heavy like menstruation, stop taking the medication as if it is a menstrual cycle. After 2 months of taking the drug, follow up with the clinic and review the liver function. 2. Highly effective progestin: medroxyprogesterone acetate, megestrol, norethindrone, etc., to be taken orally once a night from the 5th day of menstrual cycle for 3-6 months. Caution: If a little vaginal bleeding occurs during the medication period, continue to take the medication; if the bleeding is more like menstruation, increase the dose of medication. Follow up after 2 months of medication and review liver function. 3. Progesterone: Take orally from the 2nd or 3rd day of menstrual cycle, 2 times/week, 1 tablet each time, for 3-6 months. Caution: If there is a little vaginal bleeding during the medication period, continue to take the medication, but if the bleeding does not stop or the bleeding is more like menstruation, the dose of progesterone should be adjusted. After 2 months of medication, follow up and recheck the liver function in outpatient clinic. 4. GnRH-a: subcutaneous or intramuscular injection, from day 1-3 of menstrual cycle, once every 4 weeks, 3-6 times in total. Caution: A little vaginal bleeding during the medication usually does not require treatment. If menopausal symptoms such as hot flashes, vaginal dryness, decreased libido, insomnia and depression occur after a period of time, these symptoms are temporary and will disappear naturally after stopping the medication. If necessary, hormone supplementation may be used to improve these symptoms.